circRNA basic information
circBase ID: hsa_circ_0012673
Name: hsa_circ_DHCR24
Synonym: -
Host Gene: hsa-miR-320a
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal human lung epithelial cell line (BEAS-2B), human lung cancer cell lines (A549, H23)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: LIMK18521
Associated microRNA: hsa-miR-320a
Biological function: facilitates lung cancer cell proliferation and invasion
Molecular mechanism: mediating hsa-miR-320a /LIMK1 pathway
Survival: -
Supported No.:
 2
Description:

Circ_0012673 was a tumor-promoter in lung cancer via acting as competing endogenous RNA to regulate LIMK1 expression by binding miR-320a.
Other information
Title:

Circular RNA hsa_circ_0012673 facilitates lung cancer cell proliferation and invasion via miR-320a/LIMK18521 axis.

Journal: Eur Rev Med Pharmacol Sci
Published: 2020/3/7
PubMed ID: 32141553