circRNA basic information
circBase ID: -
Name: hsa_circ_SMAD7
Synonym: circ-SMAD7
Host Gene: -
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: EMT-related proteins
Associated microRNA: -
Biological function: inhibit cell migration and invasion
Molecular mechanism: -
Survival: better
Supported No.:
 1
Description:

circ-SMAD7 could inhibit cell migration and invasion of CRC by suppressing the EMT process, which might offer a potential therapeutic target for CRC.
Other information
Title:

Circular RNA circ-SMAD7 is downregulated in colorectal cancer and suppresses tumor metastasis by regulating epithelial mesenchymal transition.

Journal: Eur Rev Med Pharmacol Sci
Published: 2020/3/7
PubMed ID: 32141541