circRNA basic information
circBase ID: hsa_circ_0009910
Name: -
Synonym: Circ_0009910
Host Gene: hsa-miR-335-5p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: cell line
Sample type details: human HCC cell lines (HepG2, HCCLM3, MHCC97L, Hep3B), human normal liver cell line (L02, HEK-293)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ROCK1
Associated microRNA: hsa-miR-335-5p
Biological function: promotes proliferation and metastasis
Molecular mechanism: targeting hsa-miR-335-5p
Survival: -
Supported No.:
 3
Description:

Circ_0009910-silenced suppressed the growth and metastasis of HCC cells through upregulating the inhibitory effect of miR-335-5p on ROCK1.
Other information
Title:

Circ_0009910 promotes proliferation and metastasis of hepatocellular carcinoma cells through miR-335-5p/ROCK1 axis.

Journal: Eur Rev Med Pharmacol Sci
Published: 2020/3/7
PubMed ID: 32141540