circRNA basic information
circBase ID: -
Name: hsa_circ_ARID1A
Synonym: -
Host Gene: hsa-miR-204-3p
 
 
 
Disease basic information
DO ID:
 0060041
DO name: autism spectrum disorder
Disease details: autism spectrum disorder
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal human astrocytes cell line (NHA), human neuroblastoma cell line (SH-SY5Y), human glioblastoma cell line (U118)
circRNA-disease information
Detected method:
Q
S
M
Detected method confidence High
Expression pattern:
UP
Associated gene: ASD risk genes (NLGN1, STAG1, HSD11B1, VIP, and UBA6)
Associated microRNA: hsa-miR-204-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

We further confirmed that some ASD risk genes (NLGN1, STAG1, HSD11B1, VIP, and UBA6) were regulated by an up-regulated circRNA (circARID1A) via sponging a down-regulated microRNA (miR-204-3p) in human neuronal cells.

Other information
Title:

Genome-wide, integrative analysis of circular RNA dysregulation and the corresponding circular RNA-microRNA-mRNA regulatory axes in autism.

Journal: Genome Res
Published: 2020/3/5
PubMed ID: 32127416