circRNA basic information
circBase ID: -
Name: hsa_circ_SMAD7
Synonym: circ-SMAD7
Host Gene: -
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: GC cell lines (BGC-823, SGC-7901, HGC27, MKN-45), human gastric epithelial cell line (GES)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: inhibits GC cell migration and invasion
Molecular mechanism: reversing epithelial-to-mesenchymal transition
Survival: -
Supported No.:
 1
Description:

These results indicate that upregulation of circ-SMAD7 inhibits GC cell migration and invasion via reversing the EMT process.
Other information
Title:

Upregulation of circular SMAD7 inhibits tumorigenesis of gastric cancer by reversing epithelial-to-mesenchymal transition.

Journal: Eur Rev Med Pharmacol Sci
Published: 2020/2/26
PubMed ID: 32096163