circRNA basic information
circBase ID: hsa_circ_0073237
Name: hsa_circ_VCAN
Synonym: -
Host Gene: hsa-miR-1183
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: cell line
Sample type details: glioma cell line (293T, U87, U251)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-1183
Biological function: facilitated proliferation, invasion and migration, and inhibited apoptosis
Molecular mechanism: function as a sponge for hsa-miR-1183
Survival: -
Supported No.:
 3
Description:

overexpression of circ_VCAN expedited carcinogenesis and reduced glioma radiosensitivity by regulating miR-1183.Circ_VCAN serves as a potential oncogene of glioma by regulating miR-1183, and plays an essential role in the radioresistance of glioma.
Other information
Title:

The circ_VCAN with radioresistance contributes to the carcinogenesis of glioma by regulating microRNA-1183.

Journal: Medicine (Baltimore)
Published: 2020/2/23
PubMed ID: 32080097