circRNA basic information
circBase ID: hsa_circ_0056836
Name: hsa_circ_None
Synonym: -
Host Gene: hsa-miR-766-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HCC cell lines (HEPG2, HUH7, SNU449, SK-HEP-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FOSL2
Associated microRNA: hsa-miR-766-3p
Biological function: increased cell migration, proliferation and invasion
Molecular mechanism: directly bound to hsa-miR-766-3p, thereby alleviating the targeted inhibition of Fos-related antigen 2 (FOSL2)
Survival: -
Supported No.:
 3
Description:

the hsa_circ_0056836 / miR-766-3p / FOSL2 axis may serve as a promising strategy for HCC treatment.
Other information
Title:

Circular RNA hsa_circ_0056836 functions an oncogenic gene in hepatocellular carcinoma through modulating miR-766-3p/FOSL2 axis.

Journal: Aging (Albany NY)
Published: 2020/2/13
PubMed ID: 32048611