circRNA basic information
circBase ID: hsa_circ_0001821
Name: hsa_circ_TCONS_00015354
Synonym: -
Host Gene: hsa-miR-149
 
 
 
Disease basic information
DO ID:
 2152
DO name: ovary epithelial cancer
Disease details: epithelial ovarian cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: human EOC cells (CAOV3, SKOV3, OVCAR3), human EOC cell (SNU119), human normal ovary surface epithelial cell (HOSEpiC)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-149
Biological function: enhances cell proliferation but inhibits cell apoptosis
Molecular mechanism: sponging hsa-miR-149
Survival: -
Supported No.:
 1
Description:

Circ-PVT1 enhances cell proliferation but inhibits cell apoptosis through sponging miR-149 in EOC cells, which suggests that circ-PVT1 may serve as a treatment target in EOC.
Other information
Title:

Circular RNA PVT1 enhances cell proliferation but inhibits apoptosis through sponging microRNA-149 in epithelial ovarian cancer.

Journal: J Obstet Gynaecol Res
Published: 2020/2/13
PubMed ID: 32048451