circRNA basic information
circBase ID: hsa_circ_0072309
Name: -
Synonym: circRNA-0072309
Host Gene: hsa-miR-665
 
 
 
Disease basic information
DO ID:
 3571
DO name: liver cancer
Disease details: liver cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal liver cell line (MIHA), HCC cell lines (Huh7, HCCLM3, Hep3B, SK-HEP-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: PI3K/AKT and Wnt/beta-catenin pathways
Associated microRNA: hsa-miR-665
Biological function: The viability, colony formation, invasive and migratory ability were inhibited by abundant circRNA-0072309
Molecular mechanism: targeting hsa-miR-665 relying on the deactivation of PI3K/AKT and Wnt/beta-catenin pathways.
Survival: better
Supported No.:
 1
Description:

The circRNA-0072309 had antitumor influences in Hep3B cell line through targeting miR-665 relying on the deactivation of PI3K/AKT and Wnt/beta-catenin pathways.
Other information
Title:

Circular RNA-0072309 has antitumor influences in Hep3B cell line by targeting microRNA-665.

Journal: Biofactors
Published: 2020/2/13
PubMed ID: 32048412