circRNA basic information
circBase ID: -
Name: hsa_circ_RBM33
Synonym: hsa_circ_0001772
Host Gene: hsa-miR-149
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human gastric cancer cell lines (AGS, SGC-7901, BGC-823, MGC-803), healthy gastric epithelial cells (GES-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: IL-6
Associated microRNA: hsa-miR-149
Biological function: promoted proliferation, migration, and invasion and Inhibits Apoptosis
Molecular mechanism: circRBM33/hsa-miR-149/IL-6 axis
Survival: -
Supported No.:
 1
Description:

circRBM33 manipulates biological function in GC cells through the circRBM33/miR-149/IL-6 axis. CircRBM33 can be used as a tumor biomarker and a possible therapeutic target in the future.
Other information
Title:

CircRBM33 regulates IL-6 to promote gastric cancer progression through targeting miR-149.

Journal: Biomed Pharmacother
Published: 2020/2/12
PubMed ID: 32044717