circRNA basic information
circBase ID: -
Name: hsa_circ_HOMER1
Synonym: -
Host Gene: hsa-miR-1322
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HCC cells (Sk_Hep_1, SMMC7721, HCCLM3, Huh_7, HepG2), normal cell line (L02)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CXCL6
Associated microRNA: hsa-miR-1322
Biological function: promoted HCC cell growth and aggressiveness
Molecular mechanism: hsa-miR-1322/CXCL6 axis.
Survival: poor
Supported No.:
 2
Description:

we found that circ-HOMER1 promoted HCC cell growth and aggressiveness by miR-1322/CXCL6 axis. This study may provide a potential prognostic indicator and therapeutic target for patients with HCC.
Other information
Title:

Circ-HOMER1 enhances the inhibition of miR-1322 on CXCL6 to regulate the growth and aggressiveness of hepatocellular carcinoma cells.

Journal: J Cell Biochem
Published: 2020/2/11
PubMed ID: 32037619