circRNA basic information
circBase ID: -
Name: hsa_circ_ATRNL1
Synonym: -
Host Gene: hsa-miR-23a-3p
 
 
 
Disease basic information
DO ID:
 50866
DO name: oral squamous cell carcinoma
Disease details: oral squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
S
Detected method confidence Low
Expression pattern:
DN
Associated gene: PTEN
Associated microRNA: hsa-miR-23a-3p
Biological function: enhanced the radiosensitivity of OSCC
Molecular mechanism: directly bind to microRNA-23a-3p (hsa-miR-23a-3p) and relieve inhibition for the target gene PTEN
Survival: -
Supported No.:
 1
Description:

circANTRL1 may function as the sponge of miR-23a-3p to promote PTEN expression and eventually contributes to OSCC radiosensitivity enhancement. This study indicates that circANTRL1 may be a novel therapeutic target to improve the efficiency of radiotherapy in OSCC.
Other information
Title:

Upregulation of Circular RNA circATRNL1 to Sensitize Oral Squamous Cell Carcinoma to Irradiation.

Journal: Mol Ther Nucleic Acids
Published: 2020/2/8
PubMed ID: 32032888