circRNA basic information
circBase ID: -
Name: hsa_circ_GFRA1
Synonym: -
Host Gene: hsa-miR-188-3p
 
 
 
Disease basic information
DO ID:
3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human NSCLC cell lines (A549, NCI-H838)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PI3K/AKT signaling pathway
Associated microRNA: hsa-miR-188-3p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
1
Description:

Our study elaborated a novel circGFRA-miR-188-3p-PI3K/AKT regulatory pathway, providing a potential diagnostic biomarker and therapeutic target for NSCLC.

Other information
Title:

circGFRA1 Enhances NSCLC Progression by Sponging miR-188-3p.

Journal: Onco Targets Ther
Published: 2020/2/6
PubMed ID: 32021297