circRNA basic information
circBase ID: -
Name: hsa_circ_MAN2B2
Synonym: -
Host Gene: hsa-miR-145
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: GC cell lines (SNU_16, AGS)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PI3K, AKT and JNK
Associated microRNA: hsa-miR-145
Biological function: promotes growth and migration of gastric cancer cells
Molecular mechanism: downregulate hsa-miR-145
Survival: -
Supported No.:
 1
Description:

This work presented the oncogenic function of circMAN2B2 in GC cells growth and migration. CircMAN2B2 exerted its function possibly through regulating miR-145 as well as PI3K/AKT and JNK pathways.
Other information
Title:

Circular RNA circMAN2B2 promotes growth and migration of gastric cancer cells by down-regulation of miR-145.

Journal: J Clin Lab Anal
Published: 2020/2/6
PubMed ID: 32020674