circRNA basic information
circBase ID: -
Name: hsa_circ_PVT1
Synonym: -
Host Gene: hsa-miR-3666
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human normal liver cell line (HL-7702), HCC cell lines (SK-HEP-1, SMMC-7721, HepG2, MHCC97H)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: Sirtuin 7 (SIRT7)
Associated microRNA: hsa-miR-3666
Biological function: promotes proliferation
Molecular mechanism: decreased hsa-miR-3666
Survival: -
Supported No.:
 3
Description:

Downregulation of circular RNA circPVT1 restricts cell growth of hepatocellular carcinoma through downregulation of Sirtuin 7 via microRNA-3666.
Other information
Title:

Downregulation of circular RNA circPVT1 restricts cell growth of hepatocellular carcinoma through downregulation of Sirtuin 7 via microRNA-3666.

Journal: Clin Exp Pharmacol Physiol
Published: 2020/2/6
PubMed ID: 32017171