circRNA basic information
circBase ID: hsa_circ_0070963
Name: hsa_circ_SCLT1
Synonym: -
Host Gene: hsa-miR-223-3p
 
 
 
Disease basic information
DO ID:
409
DO name: liver disease
Disease details: liver fibrosis
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human HSC cell line (LX2)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
DN
Associated gene: LEMD3
Associated microRNA: hsa-miR-223-3p
Biological function: inhibits liver fibrosis
Molecular mechanism: regulate hsa-miR-223-3p and LEMD3
Survival: -
Supported No.:
2
Description:

hsa_circ_0070963 appeared to function as a miR-223-3p sponge that inhibited HSC activation in liver fibrosis via regulation of miR-223-3p and LEMD3.

Other information
Title:

Hsa_circ_0070963 inhibits liver fibrosis via regulation of miR-223-3p and LEMD3.

Journal: Aging (Albany NY)
Published: 2020/2/1
PubMed ID: 32003753