circRNA basic information
circBase ID: hsa_circ_0141206
Name: hsa_circ_VRK1
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: breast cancer cell lines (BT474, MCF7, MDA_MB_453, MDA_MB_231)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: inhibits cell proliferation but promotes apoptosis
Molecular mechanism: -
Survival: better
Supported No.:
 2
Description:

Circ-VRK1 is downregulated in tumour tissues and associated with reduced tumour stage as well as better survival, and it inhibits cell proliferation but promotes cell apoptosis in breast cancer.
Other information
Title:

Circular RNA VRK1 correlates with favourable prognosis, inhibits cell proliferation but promotes apoptosis in breast cancer.

Journal: J Clin Lab Anal
Published: 2020/1/24
PubMed ID: 31970831