circRNA basic information
circBase ID: -
Name: hsa_circ_FAM114A2
Synonym: -
Host Gene: hsa-miR-762
 
 
 
Disease basic information
DO ID:
 4006
DO name: bladder urothelial carcinoma
Disease details: bladder urothelial carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: T24, J82, 5637, SV-HUC-1, 293T
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: NP63 (main isoform of TP63 in UCB)
Associated microRNA: hsa-miR-762
Biological function: inhibited the migration, invasion and proliferation
Molecular mechanism: increase the expression of _NP63 (main isoform of TP63 in UCB) by sponging hsa-miR-762
Survival: better
Supported No.:
 2
Description:

circFAM114A2 might serve as a competing endogenous RNA (ceRNA) of miR-762 in regulating the expression of _NP63, thus suppressed UCB progression through circFAM114A2/miR-762/_NP63 axis.
Other information
Title:

Circular RNA FAM114A2 suppresses progression of bladder cancer via regulating _NP63 by sponging miR-762.

Journal: Cell Death Dis
Published: 2020/1/24
PubMed ID: 31969560