circRNA basic information
circBase ID: hsa_circ_0004277
Name: hsa_circ_WDR37
Synonym: -
Host Gene: hsa-miR-512-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal human colonic epithelial cell line (NCM460), CRC cell lines (SW620, LoVo, HCT 116, HT_29)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PTMA
Associated microRNA: hsa-miR-512-5p
Biological function: promoted proliferation
Molecular mechanism: upregulated PTMA by sponging hsa-miR-512-5p
Survival: -
Supported No.:
 1
Description:

our study showed that circ-0004277 promoted the proliferation of colorectal cancer cells as a miR-512-5p sponge to upregulate the PTMA expression.
Other information
Title:

Circular RNA hsa_circ_0004277 contributes to malignant phenotype of colorectal cancer by sponging miR-512-5p to upregulate the expression of PTMA.

Journal: J Cell Physiol
Published: 2020/1/22
PubMed ID: 31960446