circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA 010567
Host Gene: -
 
 
 
Disease basic information
DO ID:
5844
DO name: myocardial infarction
Disease details: myocardial Infarction
Species: rat
Species details: rat
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TGF-beta1 and Smad3
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
1
Description:

CircRNA 010567 siRNA can improve the cardiac function, alleviate the MF, and inhibit the myocardial apoptosis, thereby further suppressing MI-induced MF, whose mechanism may be related to the inhibition on the TGF-beta1 signaling pathway.

Other information
Title:

CircRNA 010567 improves myocardial infarction rats through inhibiting TGF-beta1.

Journal: Eur Rev Med Pharmacol Sci
Published: 2020/1/21
PubMed ID: 31957851