circRNA basic information
circBase ID: hsa_circ_0084043
Name: -
Synonym: circ_0084043
Host Gene: hsa-miR-429
 
 
 
Disease basic information
DO ID:
 1909
DO name: melanoma
Disease details: melanoma
Species: human
Species details: human
Sample type: cell line
Sample type details: human melanoma cell lines (A375 , SK-MEL-28), normal human keratinocyte cell line (HaCAT)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TRIB2
Associated microRNA: hsa-miR-429
Biological function: promote cell proliferation, migration and invasion, but inhibit apoptosis
Molecular mechanism: hsa-miR-429/tribbles homolog 2 axis
Survival: -
Supported No.:
 3
Description:

Knockdown of circ_0084043 suppressed the malignant development of melanoma presumably through modulating miR429/TRIB2 axis and inactivating Wnt/beta-catenin signaling pathway.
Other information
Title:

Knockdown of circ_0084043 suppresses the development of human melanoma cells through miR-429/tribbles homolog 2 axis and Wnt/beta-catenin pathway.

Journal: Life Sci
Published: 2020/1/19
PubMed ID: 31954160