circRNA basic information
circBase ID: hsa_circ_0025033
Name: hsa_circ_FOXM1
Synonym: -
Host Gene: hsa-miR-1179
 
 
 
Disease basic information
DO ID:
 3969
DO name: thyroid gland papillary carcinoma
Disease details: papillary thyroid cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human PTC cell lines (K1, IHH-4, BCPAP, TCP-1), human thyroid follicular epithelial cells (Nthy-ori 3-1)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: HMGB1
Associated microRNA: hsa-miR-1179
Biological function: -
Molecular mechanism: hsa-miR-1179/HMGB1 pathway
Survival: -
Supported No.:
 2
Description:

Our study demonstrated that circFOXM1 modulates cancer progression through the miR-1179/HMGB1 pathway in PTC. Our findings indicate that circFOXM1 may serve as a promising therapeutic target for the treatment of PTC patients.
Other information
Title:

Circular RNA circFOXM1 Plays a Role in Papillary Thyroid Carcinoma by Sponging miR-1179 and Regulating HMGB1 Expression.

Journal: Mol Ther Nucleic Acids
Published: 2020/1/18
PubMed ID: 31951855