circRNA basic information
circBase ID: hsa_circ_0057481
Name: hsa_circ_PMS1
Synonym: -
Host Gene: hsa-miR-200c
 
 
 
Disease basic information
DO ID:
 2600
DO name: laryngeal carcinoma
Disease details: laryngeal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: laryngeal carcinoma cells (HEP-2, TU212)
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: ZEB1
Associated microRNA: hsa-miR-200c
Biological function: promotes laryngeal cancer proliferation and migration
Molecular mechanism: increase the expression of ZEB1
Survival: -
Supported No.:
 1
Description:

Our findings showed that hsa_circ_0057481 might act as a novel therapeutic target in laryngeal cancer.
Other information
Title:

Hsa_circ_0057481 promotes laryngeal cancer proliferation and migration by modulating the miR-200c/ZEB1 axis.

Journal: Int J Clin Exp Pathol
Published: 2020/1/15
PubMed ID: 31933802