circRNA basic information
circBase ID: -
Name: hsa_circ_LARP4
Synonym: circ_LARP4
Host Gene: hsa-miR-513b-5p
 
 
 
Disease basic information
DO ID:
 2394
DO name: ovarian cancer
Disease details: ovarian cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: human ovarian carcinoma cells (SKOV3, A2780, SW626, OVCAR3, OVCAR4), human ovarian surface epithelial cell (HOSEpiC)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: LARP4
Associated microRNA: hsa-miR-513b-5p
Biological function: hamper cell proliferation and migration
Molecular mechanism: sponging hsa-miR-513b-5p to regulate the expression of LARP4
Survival: -
Supported No.:
 2
Description:

Circ_LARP4 could hamper cell proliferation and migration by sponging miR-513b-5p to regulate the expression of LARP4. This research may provide some referential value to OC treatment.
Other information
Title:

Up-regulation of circ_LARP4 suppresses cell proliferation and migration in ovarian cancer by regulating miR-513b-5p/LARP4 axis.

Journal: Cancer Cell Int
Published: 2020/1/9
PubMed ID: 31911757