circRNA basic information
circBase ID: -
Name: hsa_circ_EPB41L5
Synonym: circ-EPB41L5
Host Gene: hsa-miR-19a
 
 
 
Disease basic information
DO ID:
 3073
DO name: brain glioblastoma multiforme
Disease details: glioblastoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human glioma cell lines (U87, T98G, A172, LN229, U251, U373)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
DN
Associated gene: EPB41L5
Associated microRNA: hsa-miR-19a
Biological function: inhibit proliferation, clone formation, migration, and invasion
Molecular mechanism: sponging hsa-miR-19a
Survival: -
Supported No.:
 1
Description:

The effects of expression of the ectopic intervention of circ-EPB41L5 or EPB41L5 on proliferation, clone formation, migration, and invasion in vitro and tumorigenesis in vivo were observed to evaluate the function of circ-EPB41L5 or EPB41L5.
Other information
Title:

Circ-EPB41L5 regulates the host gene EPB41L5 via sponging miR-19a to repress glioblastoma tumorigenesis.

Journal: Aging (Albany NY)
Published: 2020/1/7
PubMed ID: 31905344