circRNA basic information
circBase ID: -
Name: -
Synonym: circRNA_101237
Host Gene: -
 
 
 
Disease basic information
DO ID:
 114
DO name: heart disease
Disease details: cardiomyocytes injury
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: primary cardiomyocyte culture
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: IGF2BP3
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

The results identified a novel circRNA_101237/let-7a-5p/IGF2BP3 axis, which regulated cardiomyocyte apoptosis via autophagy regulation, as a potential therapeutic target for the management of cardiovascular diseases.
Other information
Title:

Circular RNA_101237 mediates anoxia/reoxygenation injury by targeting let_7a_5p/IGF2BP3 in cardiomyocytes.

Journal: Int J Mol Med
Published: 2020/1/3
PubMed ID: 31894303