circRNA basic information
circBase ID: -
Name: hsa_circ_NFIX
Synonym: -
Host Gene: hsa-miR-378e
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: cell line
Sample type details: human astrocyte cell line (HA), glioma cell lines (T98, U251, SW1783, A172)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RPN2
Associated microRNA: hsa-miR-378e
Biological function: promote cell proliferation
Molecular mechanism: hsa-miR-378e/RPN2 axis
Survival: poor
Supported No.:
 2
Description:

Knockdown of circNFIX inhibits progression of glioma in vitro and in vivo by increasing miR-378e and decreasing RPN2, providing a novel mechanism for understanding the pathogenesis of glioma.
Other information
Title:

CircNFIX promotes progression of glioma through regulating miR-378e/RPN2 axis.

Journal: J Exp Clin Cancer Res
Published: 2020/1/1
PubMed ID: 31888753