circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-192-5p
 
 
 
Disease basic information
DO ID:
 4195
DO name: hyperglycemia
Disease details: hyperglycemia and insulin homeostasis
Species: human
Species details: human
Sample type: cell line
Sample type details: human hepatocellular carcinoma (HepG2, Huh7)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FOXO1
Associated microRNA: hsa-miR-192-5p
Biological function: contributes to hyperglycemia and insulin resistance
Molecular mechanism: sponging hsa-miR-192-5p and up-regulating FOXO1
Survival: -
Supported No.:
 1
Description:

the present study demonstrated that circHIPK3 contributes to hyperglycemia and insulin resistance by sponging miR-192-5p and up-regulating FOXO1.
Other information
Title:

Circular RNA HIPK3 contributes to hyperglycemia and insulin homeostasis by sponging miR-192-5p and upregulating transcription factor forkhead box O1.

Journal: Endocr J
Published: 2019/12/26
PubMed ID: 31875589