circRNA basic information
circBase ID: -
Name: hsa_circ_CCT3
Synonym: -
Host Gene: hsa-miR-613
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human CRC cells (HCT116, SW480), 293T cells
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: WNT3, VEGFA
Associated microRNA: hsa-miR-613
Biological function: enhance Colorectal Cancer Metastasisv
Molecular mechanism: hsa-miR-613/WNT3 or hsa-miR-613/VEGFA
Survival: poor
Supported No.:
 2
Description:

we propose that circCCT3 contributes to CRC metastasis via miR-613/WNT3 or miR-613/VEGFA, promoting the development of therapeutical approaches for treating CRC.
Other information
Title:

circCCT3 Modulates Vascular Endothelial Growth Factor A and Wnt Signaling to Enhance Colorectal Cancer Metastasis Through Sponging miR-613.

Journal: DNA Cell Biol
Published: 2019/12/21
PubMed ID: 31859543