circRNA basic information
circBase ID: hsa_circ_0001801
Name: -
Synonym: circ-0001801
Host Gene: hsa-miR-628-5p
 
 
 
Disease basic information
DO ID:
 3073
DO name: brain glioblastoma multiforme
Disease details: glioblastoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: LN229, T98, U251, BT325
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HMGB3
Associated microRNA: hsa-miR-628-5p
Biological function: promote cell proliferation, migration, invasion and epithelial to mesenchymal transition
Molecular mechanism: absorbing hsa-miR-628-5p and facilitating HMGB3 expression
Survival: -
Supported No.:
 1
Description:

Overexpression of circ-00018 01 accelerates cell proliferation, migration, invasion and EMT in GBM by absorbing miR-628-5p and facilitating HMGB3 expression, representing promising targeted therapy for GBM.
Other information
Title:

Circ-0001801 contributes to cell proliferation, migration, invasion and epithelial to mesenchymal transition (EMT) in glioblastoma by regulating miR-628-5p/HMGB3 axis.

Journal: Eur Rev Med Pharmacol Sci
Published: 2019/12/21
PubMed ID: 31858556