circRNA basic information
circBase ID: hsa_circ_0091579
Name: -
Synonym: circ_0091579
Host Gene: hsa-miR-490-3p
 
 
 
Disease basic information
DO ID:
 3571
DO name: liver cancer
Disease details: liver cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human hepatoma cell lines (HepG2, Huh7, Hep-3B, QGY-77), immortal normal liver cell line (LO2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-490-3p
Biological function: promotes proliferative ability and metastasis
Molecular mechanism: regulating microRNA-490-3p
Survival: -
Supported No.:
 1
Description:

circ_0091579 is abnormally highly expressed in LCa tissues and cells. Down-regulation of circ_0091579 can inhibit the proliferative ability and metastasis of HCC cells by regulating microRNA-490-3p, thus accelerating the progress of the tumor.
Other information
Title:

Circ_0091579 promotes proliferative ability and metastasis of liver cancer cells by regulating microRNA-490-3p.

Journal: Eur Rev Med Pharmacol Sci
Published: 2019/12/17
PubMed ID: 31841181