circRNA basic information
circBase ID: -
Name: hsa_circ_CLK3
Synonym: -
Host Gene: hsa-miR-320a
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human cervical cancer cell lines (SiHa, HeLa, CaSki, C-33A, MS751)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FoxM1
Associated microRNA: hsa-miR-320a
Biological function: enhanced cell proliferation, migration and invasion
Molecular mechanism: sponging hsa-miR-320a and promoting FoxM1 expression.
Survival: -
Supported No.:
 1
Description:

circCLK3 may serve as a novel diagnostic biomarker for disease progression and a promising molecular target for early diagnoses and treatments of cervical cancer.
Other information
Title:

The novel circCLK3/miR-320a/FoxM1 axis promotes cervical cancer progression.

Journal: Cell Death Dis
Published: 2019/12/14
PubMed ID: 31831728