circRNA basic information
circBase ID: -
Name: hsa_circ_AMOTL1
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: human breast cancer cells (MDA-MB-231)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 2
Description:

circAMOTL1 may play an important role in the PAX resistance of breast cancer cells via regulation of AKT pathway, facilitation of anti-apoptotic protein and inhibition of pro-apoptotic protein.
Other information
Title:

Posttranscriptional regulation of AKT by circular RNA angiomotin- like 1 mediates chemoresistance against paclitaxel in breast cancer cells.

Journal: Aging (Albany NY)
Published: 2019/12/11
PubMed ID: 31819016