circRNA basic information
circBase ID: -
Name: hsa_circ_ZNF292
Synonym: has-circRNA-403658
Host Gene: -
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: normal bladder epithelial cells (CCC-HB-2), bladder cancer cell lines (SW780, 5637, T24, J82, RT4)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: -
Biological function: increased cell proliferation and inhibited cell apoptosis
Molecular mechanism: activate of LDHA
Survival: -
Supported No.:
 1
Description:

We demonstrated that has-circRNA-403658 was an important circRNA that upregulated in bladder cancer cells under hypoxia, and higher has-circRNA-403658 levels were associated with poorer survival outcome.
Other information
Title:

Hypoxia-induced circular RNA has_circRNA_403658 promotes bladder cancer cell growth through activation of LDHA.

Journal: Am J Transl Res
Published: 2019/12/10
PubMed ID: 31814891