circRNA basic information
circBase ID: hsa_circ_0000291
Name: hsa_circ_CD44
Synonym: -
Host Gene: hsa-miR-183
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: human GC cell lines (MGC-803, BGC823, SGC-7901, MKN-28), gastric epithelial cell (GES-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ITGB1
Associated microRNA: hsa-miR-183
Biological function: promote proliferation, migration
Molecular mechanism: activate integrin beta 1 (ITGB1) expression via hsa-miR-183 sponging,
Survival: -
Supported No.:
 2
Description:

hsa_circ_0000291 knockdown inhibited GC cell metastasis and growth by regulating the miR-183/ITGB1 axis.
Other information
Title:

Downregulated Circular RNA hsa_circ_0000291 Suppresses Migration And Proliferation Of Gastric Cancer Via Targeting The miR-183/ITGB1 Axis.

Journal: Cancer Manag Res
Published: 2019/12/10
PubMed ID: 31814763