circRNA basic information
circBase ID: hsa_circ_0001038
Name: hsa_circ_POLR1A
Synonym: -
Host Gene: hsa-miR-337-3p
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human CC cells (HeLa, SiHa, C-33A, SW756), normal cell line (HcerEpic)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: cyclin-M3
Associated microRNA: hsa-miR-337-3p
Biological function: increased cell proliferation, migration and invasion, and inhibited cell apoptosis
Molecular mechanism: hsa_circ_0001038 could sponge hsa-miR-337-3p to release its suppression on cyclin-M3 (CNNM3) and metastasis-associated in colon cancer 1 (MACC1)
Survival: poor
Supported No.:
 1
Description:

hsa_circ_0001038 plays an oncogenic role in CC cells partly by activating CNNM3 and MACC1.
Other information
Title:

Overexpression of circular RNA hsa_circ_0001038 promotes cervical cancer cell progression by acting as a ceRNA for miR-337-3p to regulate cyclin-M3 and metastasis-associated in colon cancer 1 expression.

Journal: Gene
Published: 2019/12/7
PubMed ID: 31809842