circRNA basic information
circBase ID: -
Name: hsa_circ_FOXO3
Synonym: circ-Foxo3
Host Gene: hsa-miR-191-5p
 
 
 
Disease basic information
DO ID:
 11054
DO name: urinary bladder cancer
Disease details: bladder cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human transitional cell carcinoma (T24, UM-UC-3, J82), normal human uroepithelial cell line (SV-HUC-1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-191-5p
Biological function: induced cell apoptosis
Molecular mechanism: interaction with hsa-miR-191-5p
Survival: -
Supported No.:
 2
Description:

circ-Foxo3 was downregulated in bladder cancer in vivo and in vitro, and promoted bladder cancer apoptosis via direct interaction with miR-191.
Other information
Title:

Circular RNA circ-Foxo3 induced cell apoptosis in urothelial carcinoma via interaction with miR-191-5p.

Journal: Onco Targets Ther
Published: 2019/12/6
PubMed ID: 31802888