circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-124-3p
 
 
 
Disease basic information
DO ID:
 1287
DO name: cardiovascular system disease
Disease details: myocardial ischemia-reperfusion injury
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-124-3p
Biological function: inhibits proliferative ability and induces apoptosis of cardiomyocytes after myocardial I/R injury
Molecular mechanism: binding to miRNA-124-3p
Survival: -
Supported No.:
 2
Description:

CircHIPK3 inhibits proliferative ability and induces apoptosis of cardiomyocytes after myocardial I/R injury by binding to miRNA-124-3p, which may serve as a potential therapeutic target for I/R.
Other information
Title:

CircHIPK3 aggravates myocardial ischemia-reperfusion injury by binding to miRNA-124-3p.

Journal: Eur Rev Med Pharmacol Sci
Published: 2019/12/5
PubMed ID: 31799682