circRNA basic information
circBase ID: -
Name: hsa_circ_DB
Synonym: circ-DB
Host Gene: hsa-miR-34a
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: GCa cell lines (BGC-823, HGC-27, AGS, MGC-803, MKN-7)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MET
Associated microRNA: hsa-miR-34a
Biological function: promotes the Proliferation and Migration
Molecular mechanism: up-regulating MET
Survival: -
Supported No.:
 1
Description:

Circ-DB may regulate MET level through microRNA-34a and affect the proliferative ability and migration of GCa cells.
Other information
Title:

Circ-DB participates in the progression of gastric cancer by competitively binding microRNA-34a to regulate the expression of MET.

Journal: Eur Rev Med Pharmacol Sci
Published: 2019/12/5
PubMed ID: 31799656