circRNA basic information
circBase ID: hsa_circ_0000285
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-599
 
 
 
Disease basic information
DO ID:
3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: cell line
Sample type details: human-derived osteoblasts cells (hFOB1.19), osteosarcoma cell lines (Saos2, MG63, U2OS, SJSA1, HOS)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TGFB2
Associated microRNA: hsa-miR-599
Biological function: enhanced the proliferative and migratory potentials of osteosarcoma
Molecular mechanism: sponging hsa-miRNA-599
Survival: -
Supported No.:
4
Description:

circ-0000285 overexpression enhanced the proliferative and migratory potentials of osteosarcoma.

Other information
Title:

Hsa_circ_0000285 functions as a competitive endogenous RNA to promote osteosarcoma progression by sponging hsa-miRNA-599.

Journal: Gene Ther
Published: 2019/12/1
PubMed ID: 31784675