circRNA basic information
circBase ID: -
Name: hsa_circ_DLGAP4
Synonym: -
Host Gene: hsa-miR-134-5p
 
 
 
Disease basic information
DO ID:
 14330
DO name: Parkinson disease
Disease details: Parkinson disease
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: human neuroblastoma cell line (SH-SY5Y), mice dopaminergic neuronal cell line (MN9D)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CREB
Associated microRNA: hsa-miR-134-5p
Biological function: exerts neuroprotective effects
Molecular mechanism: activate of CREB signaling
Survival: -
Supported No.:
 1
Description:

circDLGAP4 exerts neuroprotective effects via modulating miR-134-5p/CREB pathway both in human and mouse.
Other information
Title:

Circular RNA circDLGAP4 exerts neuroprotective effects via modulating miR-134-5p/CREB pathway in Parkinson disease.

Journal: Biochem Biophys Res Commun
Published: 2019/11/26
PubMed ID: 31761328