circRNA basic information
circBase ID: -
Name: hsa_circ_TCF4.85
Synonym: circ-TCF4.85
Host Gene: hsa-miR-486-5p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human 293T cell, human normal liver cell (L_02), human HCC cell lines (SMMC_7721, Huh_7, SK_Hep_1), hepatoblastoma_derived cell line (HepG2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ABCF2
Associated microRNA: hsa-miR-486-5p
Biological function: promote proliferation, invasion, and migration, while inhibit apoptosis
Molecular mechanism: target hsa-miR-486-5p
Survival: -
Supported No.:
 1
Description:

our results reveal that silencing of circ-TCF4.85 suppresses HCC progression via miR-486-5p-targeted inhibition of ABCF2.
Other information
Title:

Circ-TCF4.85 silencing inhibits cancer progression through microRNA-486-5p-targeted inhibition of ABCF2 in hepatocellular carcinoma.

Journal: Mol Oncol
Published: 2019/11/24
PubMed ID: 31758671