circRNA basic information
circBase ID: hsa_circ_0000003
Name: -
Synonym: circ_0000003
Host Gene: hsa-miR-338-3p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human NSCLC cell lines (A549, H1650, H1299, H358, H226), normal bronchial epithelial cells (BEAS-2B)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: IRS2
Associated microRNA: hsa-miR-338-3p
Biological function: promotes the proliferation and metastasis
Molecular mechanism: functioned as endogenous competitive RNA and directly targeted hsa-miR-338-3p to positively regulated IRS2 expression
Survival: -
Supported No.:
 1
Description:

Circ_0000003 promotes the proliferation and metastasis of NSCLC cells via modulating miR-338-3p/IRS2 axis.
Other information
Title:

Circ_0000003 promotes the proliferation and metastasis of non-small cell lung cancer cells via miR-338-3p/insulin receptor substrate 2.

Journal: Cell Cycle
Published: 2019/11/19
PubMed ID: 31736412