circRNA basic information
circBase ID: -
Name: hsa_circ_Atp9b
Synonym: -
Host Gene: hsa-miR-27a
 
 
 
Disease basic information
DO ID:
 552
DO name: pneumonia
Disease details: lps-caused inflammation
Species: human
Species details: human
Sample type: cell line
Sample type details: human lung fibroblast cell line (MRC-5)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-27a
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

LPS triggered adverse inflammation response by elevating the biogenesis of circAtp9b which caused a repressive role in miR-27a expression.
Other information
Title:

circAtp9b knockdown alleviates LPS-caused inflammation provided that microRNA-27a is upregulated.

Journal: Int Immunopharmacol
Published: 2019/11/19
PubMed ID: 31735661