circRNA basic information
circBase ID: -
Name: hsa_circ_HuR
Synonym: circ-HuR
Host Gene: -
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human embryonic kidney cells (HEK293T), gastric cancer cell lines (AGS), MKN-45, MKN-74, NCI-N87
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: CNBP
Associated microRNA: -
Biological function: inhibited cell proliferation, migration and invasion
Molecular mechanism: suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation.
Survival: -
Supported No.:
 1
Description:

Circ-HuR serves as a tumor suppressor to inhibit CNBP-facilitated HuR expression and gastric cancer progression.
Other information
Title:

Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation.

Journal: Mol Cancer
Published: 2019/11/14
PubMed ID: 31718709