circRNA basic information
circBase ID: -
Name: hsa_circ_AGFG1
Synonym: -
Host Gene: hsa-miR-370-3p
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: HeLa, C-33a, SiHa, HCC94, End1/E6E7 (normal cervical cell line)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RAF1
Associated microRNA: hsa-miR-370-3p
Biological function: increased cell proliferation, migration
Molecular mechanism: promote RAF1 expression by absorbing hsa-miR-370-3p, thereby activating RAF/MEK/ERK pathway
Survival: -
Supported No.:
 1
Description:

circAGFG1 promoted proliferation and migration of CC cells via enhancing the activity of RAF/MEK/ERK pathway by sponging miR-370-3p and further regulating RAF1.
Other information
Title:

CircAGFG1 promotes cervical cancer progression via miR-370-3p/RAF1 signaling.

Journal: BMC Cancer
Published: 2019/11/11
PubMed ID: 31703640