circRNA basic information
circBase ID: -
Name: hsa_circ_FOXO1
Synonym: circ-FOXP1
Host Gene: hsa-miR-875-3p, hsa-miR-421
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HCC cell lines (SNU-387, HepG2, Hep3B, Huh7, SMMC-7721, HCCLM3), normal hepatocytes (LO2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SOX9
Associated microRNA: hsa-miR-875-3p, hsa-miR-421
Biological function: promotes the proliferation
Molecular mechanism: upregulate oncogenic transcription factor SOX9
Survival: poor
Supported No.:
 1
Description:

circ-FOXP1 is a novel driver for the tumorigenesis and aggressive progression of HCC.
Other information
Title:

Circular RNA circ-FOXP1 induced by SOX9 promotes hepatocellular carcinoma progression via sponging miR-875-3p and miR-421.

Journal: Biomed Pharmacother
Published: 2019/11/8
PubMed ID: 31698267