circRNA basic information
circBase ID: hsa_circ_0008450
Name: hsa_circ_CMTM3
Synonym: -
Host Gene: hsa-miR-214-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human normal liver cell line (L02), human HCC cell lines (SMMC7721, Sk-Hep-1, HepG2, Huh-7, HCCLM3)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: EZH2
Associated microRNA: hsa-miR-214-3p
Biological function: promote cell proliferation, invasion, and migration
Molecular mechanism: promoted the expression of EZH2 protein through sponging hsa-miR-214-3p
Survival: -
Supported No.:
 3
Description:

Knockdown of hsa_circ_0008450 inhibits HCC progression by regulating miR-214-3p/EZH2 axis.
Other information
Title:

Silencing Of hsa_circ_0008450 Represses Hepatocellular Carcinoma Progression Through Regulation Of microRNA-214-3p/EZH2 Axis.

Journal: Cancer Manag Res
Published: 2019/11/7
PubMed ID: 31695501