circRNA basic information
circBase ID: hsa_circ_0092306
Name: hsa_circ_CCS
Synonym: -
Host Gene: hsa-miR-197-3p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human gastric carcinoma cell lines (MKN-45, MKN7, HGC-27, AZ521), normal gastric mucosal epithelial cell line (GES 1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PRKCB
Associated microRNA: hsa-miR-197-3p
Biological function: increased cell proliferation, migration and invasion, and inhibited cell apoptosis
Molecular mechanism: hsa_circ_0092306 inhibited tumor suppressor hsa-miR-197-3p expression but promoted tumor promotor protein kinase C beta (PRKCB) expression
Survival: -
Supported No.:
 1
Description:

hsa_circ_0092306 promoted the development of GC by regulating the pathway of miR-197-3p/PRKCB in MKN-45 cells.
Other information
Title:

hsa_circ_0092306 Targeting miR-197-3p Promotes Gastric Cancer Development by Regulating PRKCB in MKN-45 Cells.

Journal: Mol Ther Nucleic Acids
Published: 2019/11/7
PubMed ID: 31689616