circRNA basic information
circBase ID: hsa_circ_0000211
Name: hsa_circ_SFMBT2
Synonym: -
Host Gene: hsa-miR-622
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: NSCLC cell lines (A549, H1299, H1650), human lung normal epithelial cell (BEAS-2B)
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: HIF1-alpha
Associated microRNA: hsa-miR-622
Biological function: promotes lung adenocarcinoma migration and invasion
Molecular mechanism: upregulated the HIF1-alpha expression by targeting hsa-miR-622
Survival: -
Supported No.:
 1
Description:

hsa-circ-0000211 promoted LAC cell migration and invasion by modulating the miR-622/HIF1-alpha networ.
Other information
Title:

A novel circular RNA, hsa-circ-0000211, promotes lung adenocarcinoma migration and invasion through sponging of hsa-miR-622 and modulating HIF1-alpha expression.

Journal: Biochem Biophys Res Commun
Published: 2019/11/2
PubMed ID: 31668923